Case 21. If You’ve Seen One, You Haven’t Seen Them All: Elite Controllers

Download MP3
Eileen welcomes Dr. Joel Blankson to review the case of 28-year-old man who is an elite controller. They discuss elite control characteristics, monitoring, and treatment, while also touching upon patient education and shared ART decision-making.

References Cited:
  • Hatano H, Yukl SA, Ferre AL, et al. Prospective antiretroviral treatment of asymptomatic, HIV-1 infected controllers. PLoS Pathog. 2013;9(10):e1003691. Epub 2013 Oct 10. PMID: 24130489.
  • Kwaa AK, Blankson JN. Immune Responses in Controllers of HIV Infection. Annu Rev Immunol. 2024 Jun;42(1):21-33. Epub 2024 Jun 14. PMID: 37827174.
  • Li JZ, Blankson JN. How elite controllers and posttreatment controllers inform our search for an HIV-1 cure. J Clin Invest. 2021 Jun 1;131(11):e149414. PMID: 34060478.
  • Li JZ, Segal FP, Bosch RJ, et al. Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers. Clin Infect Dis. 2020 Apr 10;70(8):1636-1642. doi: 10.1093/cid/ciz442. PMID: 31131858

Case 21. If You’ve Seen One, You Haven’t Seen Them All: Elite Controllers
Broadcast by